The deejay, whose given name is Sean Paul Henriques, had two songs in the British national chart this year: What About Us, which was done with British girl group The Saturdays, and The Other Side of Love
Deejay Stylo G, a Jamaican singer based in London, Mavado, Tarrus Riley and Popcaan were the other nominees in the Best Reggae Act block.
Stylo G, whose given name is Jason McDermott, had a Top 20 British hit this year with Soundbwoy. He and Sean Paul were front-runners for the award.
The concept of Kanya King and Andy Ruffell, the MOBOs were first held in 1996. It honours the year’s top performers of Afro-themed music.